Appearance of Acute Myelogenous Leukemia (AML) in a Patient with Breast Cancer after Adjuvant Chemotherapy: Case Report and Review of the Literature

AUTHORS

Mehrdad Payandeh 1 , Reza Khodarahmi 2 , Masoud Sadeghi 3 , * , Edris Sadeghi 3

1 Dept. of Hematology, Oncology, Kermanshah University of Medical Sciences, Kermanshah, Iran

2 Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

3 Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran

How to Cite: Payandeh M, Khodarahmi R, Sadeghi M, Sadeghi E. Appearance of Acute Myelogenous Leukemia (AML) in a Patient with Breast Cancer after Adjuvant Chemotherapy: Case Report and Review of the Literature, Int J Cancer Manag. 2015 ; 8(2):e80601.

ARTICLE INFORMATION

International Journal of Cancer Management: 8 (2); e80601
Published Online: April 30, 2015
Article Type: Case Report
Received: February 07, 2015
Accepted: February 22, 2015

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Abstract

Acute Myelogenous Leukemia (AML) is an aggressive hematologic malignancy that cause by abnormal proliferation and accumulation of hematopoietic progenitor cells. A 37-year-old woman referred to oncologic clinic with a self-detected mass and pain in her left breast. The stage of tumor was ΙΙΙA. She was treated with the combination of anthracycline and cyclophosphamide for four courses, followed by four courses of paclitaxel with trastuzumab for one year. After 18 months of the first treatment for breast cancer, her bone marrow biopsy was compatible with AML-M2. Here, we are reporting a young woman case with breast cancer that developed AML malignancy during short interval of therapy.

Keywords

Acute myelogenous leukemia Cyclophosphamide Paclitaxel

© 2015, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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