Gastrointestinal Stromal Tumors: Epidemiology and Treatment Outcomes

AUTHORS

Hassan Peyvandi 1 , * , E Haji Nasrollah 2 , SA Mousavian 3 , P Daryaii 4 , R Yeganeh 2 , A Davati 5 , GR Ghanei 6

1 Assistant professor of general surgery, Shahid Beheshti University (MC), Loghman Medical Center, Iran

2 Associate professor of general surgery, Shahid Beheshti University (MC), Loghman Medical Center, Iran

3 Resident of general surgery, Shahid Beheshti University (MC), Loghman Medical Center, Iran

4 Assistant professor of general surgery, Tehran University of Medical Sciences, Cancer Institute, Iran

5 Assistant professor of public medicine- Shahed Medical School, Iran

6 Resident of general surgery, Tehran University of Medical Sciences, Sina Medical Center, Iran

How to Cite: Peyvandi H, Haji Nasrollah E, Mousavian S, Daryaii P, Yeganeh R, et al. Gastrointestinal Stromal Tumors: Epidemiology and Treatment Outcomes , Int J Cancer Manag. 2009 ; 2(3):e80566.

ARTICLE INFORMATION

International Journal of Cancer Management: 2 (3); e80566
Published Online: September 30, 2009
Article Type: Research Article
Received: September 30, 2009
Accepted: September 30, 2009

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Abstract

Introduction: Numerous studies have investigated the prevalence, incidence and clinical manifestations of gastrointestinal stromal tumors (GISTs). However, little is known about GISTs in Iran. This pioneer study focuses on description of 36 patients with GISTs in Iran.

Methods: A database was created for 36 patients suffering from GIST who were treated in Loghman Medical Center and Tehran Cancer Institute in Tehran, Iran. Information on age, sex, clinical manifestations, treatment and outcomes were recorded and analyzed using SPSS version 13.

Results: Patients had an average age of 60 years; and 16 of them were males. The disease was most commonly manifested by abdominal mass, weight loss, and anemia. Twenty one patients had a mass smaller than 10cm; and in 33 patients KIT test was positive. In the follow-up, 5 patients experienced relapse and 3 succumbed due to advanced cancer.

Conclusion: Primary results showed that GISTs might have different manifestations and incidence in Iran compared to other parts of the world. We hope that this study could serve as a starting point for the better understanding and classification of this disease in Iran and for development of improved management strategies.

Keywords

gastrointestinal stromal tumors (gist) surgery Iran

© 2009, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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