A Study of Contractility of Proximal Surgical Margin in Esophageal Cancer

AUTHORS

Jalaluddin Khoshnevis 1 , * , Afshin Moradi 2 , Eznollah Azargashb 3 , Barmak Gholizade 1 , Mohammad Reza Sobhiyeh 1

1 Cancer Research Center, Shahid Beheshti University of Medical Sciences, Dept. of General and Vascular Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3 Cancer Research Center, Shahid Beheshti University of Medical Sciences, Dept. of Health and Social Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

How to Cite: Khoshnevis J, Moradi A, Azargashb E, Gholizade B, Sobhiyeh M R. A Study of Contractility of Proximal Surgical Margin in Esophageal Cancer, Int J Cancer Manag. 2013 ; 6(1):e80380.

ARTICLE INFORMATION

International Journal of Cancer Management: 6 (1); e80380
Published Online: March 30, 2013
Article Type: Research Article
Received: September 22, 2012
Accepted: November 18, 2012

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Abstract

Background: The marginal length from main tumor in esophageal cancer is a considerable issue regarding surgical management and adjuvant treatment; so we decided to study the contractility effect on the proximal surgical margin after immersing it in10% buffered formalin as a fixative.

Methods: The proximal marginal length of ten sequential patients with esophageal cancer who underwent transhiatal esophagectomy were studied, on the operating table as fresh specimens, immediately after resection, and next 24, 48 and 72 hours after immersing in 10% buffered formalin.

Results: The contraction continued through the day 3, the mean contractility after one day was about 27%, after two days was 33% and after three days was 38%.

Conclusion: This study shows how the proximal esophageal margin can vary by the time, after immersing in 10% buffered formalin and should be considered in every settings and reporting documents by pathologists.

Keywords

Esophageal cancer Marginal safety Contractility

© 2013, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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