International Journal of Cancer Management

Published by: Kowsar

Association between VDR Gene Polymorphisms (rs 1544410, rs 7975232, rs 2228570, rs 731236 and rs 11568820) and Susceptibility to Breast Cancer in a Sample of Southeastern Iranian Population

Seyed Mehdi Hashemi 1 , Narges Arbabi 2 , * , Mohammad Hashemi 3 , Mohammad Ali Mashhadi 1 , Abolghasem Allahyari 4 and Masoud Sadeghi 5
Authors Information
1 Department of Internal Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
2 Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
3 Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
4 Department of Hematology and Medical Oncology, Mashhad University of Medical Sciences, Mashhad, Iran
5 Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Article information
  • International Journal of Cancer Management: March 2017, 10 (3); e8807
  • Published Online: March 26, 2017
  • Article Type: Research Article
  • Received: September 7, 2016
  • Revised: December 4, 2016
  • Accepted: March 1, 2017
  • DOI: 10.5812/ijcm.8807

To Cite: Hashemi S M, Arbabi N, Hashemi M, Mashhadi M A, Allahyari A, et al. Association between VDR Gene Polymorphisms (rs 1544410, rs 7975232, rs 2228570, rs 731236 and rs 11568820) and Susceptibility to Breast Cancer in a Sample of Southeastern Iranian Population, Int J Cancer Manag. 2017 ;10(3):e8807. doi: 10.5812/ijcm.8807.

Abstract
Copyright © 2017, International Journal of Cancer Management. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Madani SH, Payandeh M, Sadeghi M, Motamed H, Sadeghi E. The correlation between Ki-67 with other prognostic factors in breast cancer: A study in Iranian patients. Indian J Med Paediatr Oncol. 2016; 37(2): 95-9[DOI][PubMed]
  • 2. Payandeh M, Sadeghi M, Sadeghi E. Differences in Prognostic Factors between Early and Late Recurrence Breast Cancers. Asian Pac J Cancer Prev. 2015; 16(15): 6575-9[DOI][PubMed]
  • 3. Chandler MR, Bilgili EP, Merner ND. A Review of Whole-Exome Sequencing Efforts Toward Hereditary Breast Cancer Susceptibility Gene Discovery. Hum Mutat. 2016; 37(9): 835-46[DOI][PubMed]
  • 4. Rahimzadeh M, Pourhoseingholi MA, Kavehie B. Survival Rates for Breast Cancer in Iranian Patients: a Meta- Analysis. Asian Pac J Cancer Prev. 2016; 17(4): 2223-7[DOI][PubMed]
  • 5. Filippini SE, Vega A. Breast cancer genes: beyond BRCA1 and BRCA2. Front Biosci (Landmark Ed). 2013; 18: 1358-72[DOI][PubMed]
  • 6. Collins A, Politopoulos I. The genetics of breast cancer: risk factors for disease. Appl Clin Genet. 2011; 4: 11-9[DOI][PubMed]
  • 7. Hashemi M, Amininia S, Ebrahimi M, Hashemi SM, Taheri M, Ghavami S. Association between hTERT polymorphisms and the risk of breast cancer in a sample of Southeast Iranian population. BMC Res Notes. 2014; 7: 895[DOI][PubMed]
  • 8. Hashemi M, Amininia S, Ebrahimi M, Hashemi SM, Yousefi J, Eskandari-Nasab E, et al. Association between LAPTM4B gene polymorphism and breast cancer susceptibility in an Iranian population. Med Oncol. 2014; 31(8): 111[DOI][PubMed]
  • 9. Hashemi M, Yousefi J, Hashemi SM, Amininia S, Ebrahimi M, Taheri M, et al. Association between Programmed Cell Death 6 Interacting Protein Insertion/Deletion Polymorphism and the Risk of Breast Cancer in a Sample of Iranian Population. Dis Markers. 2015; 2015: 854621[DOI][PubMed]
  • 10. Chakraborty A, Mishra AK, Soni A, Regina T, Mohil R, Bhatnagar D, et al. Vitamin D receptor gene polymorphism(s) and breast cancer risk in north Indians. Cancer Detect Prev. 2009; 32(5-6): 386-94[DOI][PubMed]
  • 11. McKay JD, McCullough ML, Ziegler RG, Kraft P, Saltzman BS, Riboli E, et al. Vitamin D receptor polymorphisms and breast cancer risk: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Cancer Epidemiol Biomarkers Prev. 2009; 18(1): 297-305[DOI][PubMed]
  • 12. Mishra DK, Wu Y, Sarkissyan M, Sarkissyan S, Chen Z, Shang X, et al. Vitamin D receptor gene polymorphisms and prognosis of breast cancer among African-American and Hispanic women. PLoS One. 2013; 8(3)[DOI][PubMed]
  • 13. Haussler MR, Haussler CA, Bartik L, Whitfield GK, Hsieh JC, Slater S, et al. Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention. Nutr Rev. 2008; 66(10 Suppl 2)-112[DOI][PubMed]
  • 14. Pulito C, Terrenato I, Di Benedetto A, Korita E, Goeman F, Sacconi A, et al. Cdx2 polymorphism affects the activities of vitamin D receptor in human breast cancer cell lines and human breast carcinomas. PLoS One. 2015; 10(4)[DOI][PubMed]
  • 15. Payandeh M, Sadeghi M, Sadeghi E, Madani SH. Expression of p53 Breast Cancer in Kurdish Women in the West of Iran: a Reverse Correlation with Lymph Node Metastasis. Asian Pac J Cancer Prev. 2016; 17(3): 1261-4[DOI][PubMed]
  • 16. Eskandari-Nasab E, Hashemi M, Amininia S, Ebrahimi M, Rezaei M, Hashemi SM. Effect of TP53 16-bp and beta-TrCP 9-bp INS/DEL polymorphisms in relation to risk of breast cancer. Gene. 2015; 568(2): 181-5[DOI][PubMed]
  • 17. Guy M, Lowe LC, Bretherton-Watt D, Mansi JL, Peckitt C, Bliss J, et al. Vitamin D receptor gene polymorphisms and breast cancer risk. Clin Cancer Res. 2004; 10(16): 5472-81[DOI][PubMed]
  • 18. Zhou ZC, Wang J, Cai ZH, Zhang QH, Cai ZX, Wu JH. Association between vitamin D receptor gene Cdx2 polymorphism and breast cancer susceptibility. Tumour Biol. 2013; 34(6): 3437-41[DOI][PubMed]
  • 19. Ingles SA, Garcia DG, Wang W, Nieters A, Henderson BE, Kolonel LN, et al. Vitamin D receptor genotype and breast cancer in Latinas (United States). Cancer Causes Control. 2000; 11(1): 25-30[DOI][PubMed]
  • 20. Rashid MU, Muzaffar M, Khan FA, Kabisch M, Muhammad N, Faiz S, et al. Association between the BsmI Polymorphism in the Vitamin D Receptor Gene and Breast Cancer Risk: Results from a Pakistani Case-Control Study. PLoS One. 2015; 10(10)[DOI][PubMed]
  • 21. Rollison DE, Cole AL, Tung KH, Slattery ML, Baumgartner KB, Byers T, et al. Vitamin D intake, vitamin D receptor polymorphisms, and breast cancer risk among women living in the southwestern U.S. Breast Cancer Res Treat. 2012; 132(2): 683-91[DOI][PubMed]
  • 22. Iqbal M, Khan TA, Maqbool SA. Vitamin D receptor Cdx-2 polymorphism and premenopausal breast cancer risk in southern Pakistani patients. PLoS One. 2015; 10(3)[DOI][PubMed]
  • 23. Dorjgochoo T, Delahanty R, Lu W, Long J, Cai Q, Zheng Y, et al. Common genetic variants in the vitamin D pathway including genome-wide associated variants are not associated with breast cancer risk among Chinese women. Cancer Epidemiol Biomarkers Prev. 2011; 20(10): 2313-6[DOI][PubMed]
  • 24. Yang B, Liu S, Yang X, Wang Y, Zhao X, Zheng D, et al. Current evidence on the four polymorphisms of VDR and breast cancer risk in Caucasian women. Meta Gene. 2014; 2: 41-9[DOI][PubMed]
  • 25. Lu D, Jing L, Zhang S. Vitamin D Receptor Polymorphism and Breast Cancer Risk: A Meta-Analysis. Medicine (Baltimore). 2016; 95(18)[DOI][PubMed]
  • 26. Tang C, Chen N, Wu M, Yuan H, Du Y. Fok1 polymorphism of vitamin D receptor gene contributes to breast cancer susceptibility: a meta-analysis. Breast Cancer Res Treat. 2009; 117(2): 391-9[DOI][PubMed]
  • 27. Curran JE, Vaughan T, Lea RA, Weinstein SR, Morrison NA, Griffiths LR. Association of A vitamin D receptor polymorphism with sporadic breast cancer development. Int J Cancer. 1999; 83(6): 723-6[DOI][PubMed]
  • 28. Chen WY, Bertone-Johnson ER, Hunter DJ, Willett WC, Hankinson SE. Associations between polymorphisms in the vitamin D receptor and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2005; 14(10): 2335-9[DOI][PubMed]
  • 29. Shahbazi S, Alavi S, Majidzadeh AK, Ghaffarpour M, Soleimani A, Mahdian R. BsmI but not FokI polymorphism of VDR gene is contributed in breast cancer. Med Oncol. 2013; 30(1): 393[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments