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Virotherapy in Cancer

AUTHORS

Gholamreza Motalleb 1 , *

1 Dept. of Biology, Faculty of Science, University of Zabol, Iran

How to Cite: Motalleb G . Virotherapy in Cancer, Int J Cancer Manag. 2013 ; 6(2):e80409.

ARTICLE INFORMATION

International Journal of Cancer Management: 6 (2); e80409
Published Online: June 30, 2013
Article Type: Review Article
Received: January 17, 2013
Accepted: April 08, 2013

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Abstract

New cancer therapies with novel mechanisms and functions are needed to treat patients with different cancers. Virotherapy is a good scenario for such treatment. The advantages of virotherapy include the potential lack of cross resistance with standard therapies and the ability to cause tumor destruction by numerous mechanisms. Oncolytic virus not only possesses unique mechanisms of action that are distinct from other treatment modalities, its self-perpetuating nature provides an ideal platform for therapeutic transgenic insertion. In this review article, a variety of oncolytic viruses in cancer gene therapy will be described.

Keywords

Cancer Oncolytic viruses Gene therapy

© 2013, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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