International Journal of Cancer Management

Published by: Kowsar

Anti-Proliferative and Apoptotic Effects of Aqueous Extract of Ziziphus Jujube in Human Thyroid Carcinoma Cell Lines (C643)

Fataneh Hashem Dabaghian 1 , 2 , Azita Hassani 3 , Navid Nayeri 4 , Asie Shojaii 1 , 2 and Maliheh Entezari 4 , *
Authors Information
1 Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, IR Iran
2 School of Traditional Medicine, Iran University of Medical Sciences, Tehran, IR Iran
3 Department of Biology, Islamic Azad University, Zanjan Branch, Zanjan, IR Iran
4 Department of Medical Biotechnology, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, IR Iran
Article information
  • International Journal of Cancer Management: July 2018, 11 (7); e65820
  • Published Online: July 1, 2018
  • Article Type: Research Article
  • Received: January 20, 2018
  • Revised: April 15, 2018
  • Accepted: June 5, 2018
  • DOI: 10.5812/ijcm.65820

To Cite: Hashem Dabaghian F, Hassani A, Nayeri N, Shojaii A, Entezari M. Anti-Proliferative and Apoptotic Effects of Aqueous Extract of Ziziphus Jujube in Human Thyroid Carcinoma Cell Lines (C643), Int J Cancer Manag. 2018 ; 11(7):e65820. doi: 10.5812/ijcm.65820.

Abstract
Copyright © 2018, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
Acknowledgements
Footnotes
References
  • 1. Sadjadi A, Nouraie M, Mohagheghi MA, Mousavi-Jarrahi A, Malekezadeh R, Parkin DM. Cancer occurrence in Iran in 2002, an international perspective. Asian Pac J Cancer Prev. 2005;6(3):359-63. [PubMed: 16236000].
  • 2. Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87-108. doi: 10.3322/caac.21262. [PubMed: 25651787].
  • 3. Hodgson NC, Button J, Solorzano CC. Thyroid cancer: is the incidence still increasing? Ann Surg Oncol. 2004;11(12):1093-7. doi: 10.1245/ASO.2004.03.066. [PubMed: 15576834].
  • 4. Bown D; Herb Society of America. Encyclopedia of Herbs and Their Uses. Dorling Kindersley; 1995.
  • 5. Aghili-Khorasani MH. Annab Makhzan al-adviah. Tehran: Research Institute for Islamic and Complementary medicine; 2008.
  • 6. Gao QH, Wu CS, Wang M. The jujube (Ziziphus jujuba Mill.) fruit: a review of current knowledge of fruit composition and health benefits. J Agric Food Chem. 2013;61(14):3351-63. doi: 10.1021/jf4007032. [PubMed: 23480594].
  • 7. Plastina P, Bonofiglio D, Vizza D, Fazio A, Rovito D, Giordano C, et al. Identification of bioactive constituents of Ziziphus jujube fruit extracts exerting antiproliferative and apoptotic effects in human breast cancer cells. J Ethnopharmacol. 2012;140(2):325-32. doi: 10.1016/j.jep.2012.01.022. [PubMed: 22301448].
  • 8. Hoshyar R, Mohaghegh Z, Torabi N, Abolghasemi A. Antitumor activity of aqueous extract of Ziziphus jujube fruit in breast cancer: An in vitro and in vivo study. Asian Pac J Reprod. 2015;4(2):116-22. doi: 10.1016/s2305-0500(15)30007-5.
  • 9. Abedini MR, Erfanian N, Nazem H, Jamali S, Hoshyar R. Anti-proliferative and apoptotic effects of Ziziphus Jujube on cervical and breast cancer cells. Avicenna J Phytomed. 2016;6(2):142-8. [PubMed: 27222827]. [PubMed Central: PMC4877962].
  • 10. Huang X, Kojima-Yuasa A, Norikura T, Kennedy DO, Hasuma T, Matsui-Yuasa I. Mechanism of the anti-cancer activity of Zizyphus jujuba in HepG2 cells. Am J Chin Med. 2007;35(3):517-32. doi: 10.1142/S0192415X0700503X. [PubMed: 17597510].
  • 11. Vahedi F, Fathi Najafi M, Bozari K. Evaluation of inhibitory effect and apoptosis induction of Zyzyphus Jujube on tumor cell lines, an in vitro preliminary study. Cytotechnology. 2008;56(2):105-11. doi: 10.1007/s10616-008-9131-6. [PubMed: 19002848]. [PubMed Central: PMC2259261].
  • 12. Hung CF, Hsu BY, Chang SC, Chen BH. Antiproliferation of melanoma cells by polysaccharide isolated from Zizyphus jujuba. Nutrition. 2012;28(1):98-105. doi: 10.1016/j.nut.2011.05.009. [PubMed: 21820868].
  • 13. Haselkorn T, Bernstein L, Preston-Martin S, Cozen W, Mack WJ. Descriptive epidemiology of thyroid cancer in Los Angeles County, 1972-1995. Cancer Causes Control. 2000;11(2):163-70. [PubMed: 10710201].
  • 14. Li N, Du XL, Reitzel LR, Xu L, Sturgis EM. Impact of enhanced detection on the increase in thyroid cancer incidence in the United States: review of incidence trends by socioeconomic status within the surveillance, epidemiology, and end results registry, 1980-2008. Thyroid. 2013;23(1):103-10. doi: 10.1089/thy.2012.0392. [PubMed: 23043274]. [PubMed Central: PMC3539256].
  • 15. Miliauskas G, Venskutonis PR, van Beek TA. Screening of radical scavenging activity of some medicinal and aromatic plant extracts. Food Chem. 2004;85(2):231-7. doi: 10.1016/j.foodchem.2003.05.007.
  • 16. Entezari M, Atabi F. Preparation and Characterization of Myristoylated Chitosan Nanogel as Carrier of Silibinin for Breast Cancer Therapy. Gallen Med J. 2017;6(2):136-44.
  • 17. Karimi R, Parivar K, Hayati Roudbari N, Vakili Sadeghi S, Hashemi M, Hayat P. Anti-proliferative and Apoptotic Effects of morin in human Leukemia cell lines (HUT-78). Int J Cell Molecul Biotechnol. 2013;2013:1-13. doi: 10.5899/2013/ijcmb-00001.
  • 18. Traub ML, De Butte-Smith M, Zukin RS, Etgen AM. Oestradiol and insulin-like growth factor-1 reduce cell loss after global ischaemia in middle-aged female rats. J Neuroendocrinol. 2009;21(12):1038-44. doi: 10.1111/j.1365-2826.2009.01927.x. [PubMed: 19840235]. [PubMed Central: PMC2862345].
  • 19. Hashemi M, Nouri Long M, Entezari M, Nafisi S, Nowroozii H. Anti-mutagenic and pro-apoptotic effects of apigenin on human chronic lymphocytic leukemia cells. Acta Med Iran. 2010;48(5):283-8. [PubMed: 21287458].
  • 20. Entezari M, Majd A, Falahian F, Mehrabian S, Hashemi M, Lajimi AA. Antimutagenicity and anticancer effects of Citrus medica fruit juice. Acta Medica Iranica. 2009;47(5):373-7.
  • 21. Newman DJ, Cragg GM, Snader KM. Natural products as sources of new drugs over the period 1981-2002. J Nat Prod. 2003;66(7):1022-37. doi: 10.1021/np030096l. [PubMed: 12880330].
  • 22. Paterson I, Anderson EA. Chemistry. The renaissance of natural products as drug candidates. Science. 2005;310(5747):451-3. doi: 10.1126/science.1116364. [PubMed: 16239465].
  • 23. Bathaie SZ, Mousavi SZ. New applications and mechanisms of action of saffron and its important ingredients. Crit Rev Food Sci Nutr. 2010;50(8):761-86. doi: 10.1080/10408390902773003. [PubMed: 20830635].
  • 24. George VC, Dellaire G, Rupasinghe HPV. Plant flavonoids in cancer chemoprevention: role in genome stability. J Nutr Biochem. 2017;45:1-14. doi: 10.1016/j.jnutbio.2016.11.007. [PubMed: 27951449].
  • 25. Ravishankar D, Rajora AK, Greco F, Osborn HM. Flavonoids as prospective compounds for anti-cancer therapy. Int J Biochem Cell Biol. 2013;45(12):2821-31. doi: 10.1016/j.biocel.2013.10.004. [PubMed: 24128857].
  • 26. Wang W, Wang J, Li N, Zhang X, Zhao W, Li J, et al. Chemopreventive flavonoids from Millettia pulchra Kurz var-laxior (Dunn) Z.Wei (Yulangsan) function as Michael reaction acceptors. Bioorg Med Chem Lett. 2015;25(5):1078-81. doi: 10.1016/j.bmcl.2015.01.009. [PubMed: 25630222].
  • 27. Biswas SK. Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox? Oxid Med Cell Longev. 2016;2016:5698931. doi: 10.1155/2016/5698931. [PubMed: 26881031]. [PubMed Central: PMC4736408].
  • 28. Clarkson PM, Thompson HS. Antioxidants: what role do they play in physical activity and health? Am J Clin Nutr. 2000;72(2 Suppl):637S-46S. doi: 10.1093/ajcn/72.2.637S. [PubMed: 10919970].
  • 29. Chen SC, Chung KT. Mutagenicity and antimutagenicity studies of tannic acid and its related compounds. Food Chem Toxicol. 2000;38(1):1-5. [PubMed: 10685008].
  • 30. Suzuki YJ, Forman HJ, Sevanian A. Oxidants as Stimulators of Signal Transduction. Free Radic Biol Med. 1997;22(1-2):269-85. doi: 10.1016/s0891-5849(96)00275-4.
  • 31. Cheng G, Bai Y, Zhao Y, Tao J, Liu Y, Tu G, et al. Flavonoids from Ziziphus jujuba Mill var. spinosa. Tetrahedron. 2000;56(45):8915-20. doi: 10.1016/s0040-4020(00)00842-5.
  • 32. Watson WH, Cai J, Jones DP. Diet and apoptosis. Annu Rev Nutr. 2000;20:485-505. doi: 10.1146/annurev.nutr.20.1.485. [PubMed: 10940343].
  • 33. Yang CS, Landau JM, Huang MT, Newmark HL. Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu Rev Nutr. 2001;21:381-406. doi: 10.1146/annurev.nutr.21.1.381. [PubMed: 11375442].
  • 34. Manson MM. Cancer prevention -- the potential for diet to modulate molecular signalling. Trends Mol Med. 2003;9(1):11-8. [PubMed: 12524205].
  • 35. Shishodia S, Sethi G, Konopleva M, Andreeff M, Aggarwal BB. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. Clin Cancer Res. 2006;12(6):1828-38. doi: 10.1158/1078-0432.CCR-05-2044. [PubMed: 16551868].
  • 36. Zhang H, Jiang L, Ye S, Ye Y, Ren F. Systematic evaluation of antioxidant capacities of the ethanolic extract of different tissues of jujube (Ziziphus jujuba Mill.) from China. Food Chem Toxicol. 2010;48(6):1461-5. doi: 10.1016/j.fct.2010.03.011. [PubMed: 20230870].
  • 37. Lee SM, Min BS, Lee CG, Kim KS, Kho YH. Cytotoxic triterpenoids from the fruits of Zizyphus jujuba. Planta Med. 2003;69(11):1051-4. doi: 10.1055/s-2003-45155. [PubMed: 14735446].
  • 38. Entezari M, Dabaghian FH, Hashemi M. The comparison of antimutagenicity and anticancer activities of Echinophora platyloba DC on acute promyelocytic leukemia cancer cells. J Cancer Res Ther. 2014;10(4):1004-7. doi: 10.4103/0973-1482.137907. [PubMed: 25579544].
  • 39. Dabaghian FH. Antimutagenicity and Anticancer Effects of Biebersteinia multifida DC. Annu Res Revi in Biol. 2014;4(6):906-13. doi: 10.9734/arrb/2014/7193.
  • 40. Piltan A, Totonchi M, Rezazadeh M, Gourabi H, Karimian L, Baghaban Eslaminejad MR, et al. Quantitative expression of BAG1, BAX and BCL-2 genes in human embryos with different fragmentation grades derived from ART. Yakhteh Med J. 2010;12:257-66.
  • 41. Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol. 2007;35(4):495-516. doi: 10.1080/01926230701320337. [PubMed: 17562483]. [PubMed Central: PMC2117903].
  • 42. MacFarlane M, Williams AC. Apoptosis and disease: a life or death decision. EMBO Rep. 2004;5(7):674-8. doi: 10.1038/sj.embor.7400191. [PubMed: 15218528]. [PubMed Central: PMC1299101].
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments