International Journal of Cancer Management

Published by: Kowsar

Evaluation of MAGE-1 Cancer-Testis Antigen Expression in Invasive Breast Cancer and its Correlation with Prognostic Factors

Mojtaba Rastgoosalami 1 , Bahram Memar 2 , Seyed Amir Aledavood 2 and Azar Fanipakdel 2 , *
Authors Information
1 Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, IR Iran
2 Cancer Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Article information
  • Iranian Journal of Cancer Prevention: August 2016, 9 (4); e4404
  • Published Online: August 15, 2016
  • Article Type: Research Article
  • Received: October 20, 2015
  • Revised: November 14, 2015
  • Accepted: August 10, 2016
  • DOI: 10.17795/ijcp-4404

To Cite: Rastgoosalami M, Memar B, Aledavood S A, Fanipakdel A. Evaluation of MAGE-1 Cancer-Testis Antigen Expression in Invasive Breast Cancer and its Correlation with Prognostic Factors, Int J Cancer Manag. 2016 ; 9(4):e4404. doi: 10.17795/ijcp-4404.

Abstract
Copyright © 2016, Iranian Journal of Cancer Prevention. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, et al. Cancer statistics, 2008. CA Cancer J Clin. 2008; 58(2): 71-96[DOI][PubMed]
  • 2. Badovinac Crnjevic T, Spagnoli G, Juretic A, Jakic-Razumovic J, Podolski P, Saric N. High expression of MAGE-A10 cancer-testis antigen in triple-negative breast cancer. Med Oncol. 2012; 29(3): 1586-91[DOI][PubMed]
  • 3. Almeida LG, Sakabe NJ, deOliveira AR, Silva MC, Mundstein AS, Cohen T, et al. CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens. Nucleic Acids Res. 2009; 37-9[DOI][PubMed]
  • 4. Hofmann O, Caballero OL, Stevenson BJ, Chen YT, Cohen T, Chua R, et al. Genome-wide analysis of cancer/testis gene expression. Proc Natl Acad Sci U S A. 2008; 105(51): 20422-7[DOI][PubMed]
  • 5. Gure AO, Chua R, Williamson B, Gonen M, Ferrera CA, Gnjatic S, et al. Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer. Clin Cancer Res. 2005; 11(22): 8055-62[DOI][PubMed]
  • 6. Velazquez EF, Jungbluth AA, Yancovitz M, Gnjatic S, Adams S, O'Neill D, et al. Expression of the cancer/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM)--correlation with prognostic factors. Cancer Immun. 2007; 7: 11[PubMed]
  • 7. Andrade VC, Vettore AL, Felix RS, Almeida MS, Carvalho F, Oliveira JS, et al. Prognostic impact of cancer/testis antigen expression in advanced stage multiple myeloma patients. Cancer Immun. 2008; 8: 2[PubMed]
  • 8. Napoletano C, Bellati F, Tarquini E, Tomao F, Taurino F, Spagnoli G, et al. MAGE-A and NY-ESO-1 expression in cervical cancer: prognostic factors and effects of chemotherapy. Am J Obstet Gynecol. 2008; 198(1): 99 e1-7[DOI][PubMed]
  • 9. Scanlan MJ, Gure AO, Jungbluth AA, Old LJ, Chen YT. Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol Rev. 2002; 188: 22-32[PubMed]
  • 10. Pelletier RM, Byers SW. The blood-testis barrier and Sertoli cell junctions: structural considerations. Microsc Res Tech. 1992; 20(1): 3-33[DOI][PubMed]
  • 11. Mashino K, Sadanaga N, Tanaka F, Yamaguchi H, Nagashima H, Inoue H, et al. Expression of multiple cancer-testis antigen genes in gastrointestinal and breast carcinomas. Br J Cancer. 2001; 85(5): 713-20[DOI][PubMed]
  • 12. Russo V, Traversari C, Verrecchia A, Mottolese M, Natali PG, Bordignon C. Expression of the MAGE gene family in primary and metastatic human breast cancer: implications for tumor antigen-specific immunotherapy. Int J Cancer. 1995; 64(3): 216-21[PubMed]
  • 13. Ghafouri-Fard S, Shamsi R, Seifi-Alan M, Javaheri M, Tabarestani S. Cancer-testis genes as candidates for immunotherapy in breast cancer. Immunotherapy. 2014; 6(2): 165-79[DOI][PubMed]
  • 14. Bolli M, Schultz-Thater E, Zajac P, Guller U, Feder C, Sanguedolce F, et al. NY-ESO-1/LAGE-1 coexpression with MAGE-A cancer/testis antigens: a tissue microarray study. Int J Cancer. 2005; 115(6): 960-6[DOI][PubMed]
  • 15. Allred DC, Harvey JM, Berardo M, Clark GM. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol. 1998; 11(2): 155-68[PubMed]
  • 16. Kruger S, Ola V, Feller AC, Fischer D, Friedrich M. Expression of cancer-testis antigen CT7 (MAGE-C1) in breast cancer: an immunohistochemical study with emphasis on prognostic utility. Pathol Oncol Res. 2007; 13(2): 91-6[PubMed]
  • 17. Rosenberg SA. Progress in human tumour immunology and immunotherapy. Nature. 2001; 411(6835): 380-4[DOI][PubMed]
  • 18. Caballero OL, Chen YT. Cancer/testis (CT) antigens: potential targets for immunotherapy. Cancer Sci. 2009; 100(11): 2014-21[DOI][PubMed]
  • 19. Bandic D, Juretic A, Sarcevic B, Separovic V, Kujundzic-Tiljak M, Hudolin T, et al. Expression and possible prognostic role of MAGE-A4, NY-ESO-1, and HER-2 antigens in women with relapsing invasive ductal breast cancer: retrospective immunohistochemical study. Croat Med J. 2006; 47(1): 32-41[PubMed]
  • 20. Kavalar R, Sarcevic B, Spagnoli GC, Separovic V, Samija M, Terracciano L, et al. Expression of MAGE tumour-associated antigens is inversely correlated with tumour differentiation in invasive ductal breast cancers: an immunohistochemical study. Virchows Arch. 2001; 439(2): 127-31[PubMed]
  • 21. Schultz-Thater E, Piscuoglio S, Iezzi G, Le Magnen C, Zajac P, Carafa V, et al. MAGE-A10 is a nuclear protein frequently expressed in high percentages of tumor cells in lung, skin and urothelial malignancies. Int J Cancer. 2011; 129(5): 1137-48[DOI][PubMed]
  • 22. Chen YT, Ross DS, Chiu R, Zhou XK, Chen YY, Lee P, et al. Multiple cancer/testis antigens are preferentially expressed in hormone-receptor negative and high-grade breast cancers. PLoS One. 2011; 6(3)[DOI][PubMed]
  • 23. Curigliano G, Viale G, Ghioni M, Jungbluth AA, Bagnardi V, Spagnoli GC, et al. Cancer-testis antigen expression in triple-negative breast cancer. Ann Oncol. 2011; 22(1): 98-103[DOI][PubMed]
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