International Journal of Cancer Management

Published by: Kowsar

Postmenopausal Choriocarcinoma: Case Report and Literature Review

Zohreh Yousefi 1 , Shohreh Saied 2 , Behrouz Davachi 3 , Alireza Rezaei 4 , * and Fatemeh Mirzamarjani 5
Authors Information
1 Professor, Department of Obstetrics and Gynecology, Fellowship of Gynecology Oncology, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
2 Resident Fellowship of Gynecology Oncology, Department of Obstetrics and Gynecology, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
3 Associate Professor, Department of Radiology, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
4 Anatomo Clinical Pathologist, Assistant Professor, Islamic Azad University of Medical Science, Mashhad, IR Iran
5 Resident of Obstetrics and Gynecology, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Article information
  • International Journal of Cancer Management: May 2017, 10 (5); e4400
  • Published Online: March 20, 2017
  • Article Type: Case Report
  • Received: December 23, 2015
  • Revised: June 18, 2016
  • Accepted: March 5, 2017
  • DOI: 10.5812/ijcm.4400

To Cite: Yousefi Z, Saied S, Davachi B, Rezaei A, Mirzamarjani F. Postmenopausal Choriocarcinoma: Case Report and Literature Review, Int J Cancer Manag. 2017 ; 10(5):e4400. doi: 10.5812/ijcm.4400.

Copyright © 2017, International Journal of Cancer Management. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Reports
3. Discussion
  • 1. Mukherjee U, Thakur V, Katiyar D, Goyal HK, Pendharkar D. Uterine choriocarcinoma in a postmenopausal woman. Med Oncol. 2006; 23(2): 301-3[DOI][PubMed]
  • 2. Gestational trophoblastic tumors. 2014;
  • 3. Cole LA. New discoveries on the biology and detection of human chorionic gonadotropin. Reprod Biol Endocrinol. 2009; 7: 8[DOI][PubMed]
  • 4. Rangwala TH, Badawi F. A profile of cases of gestational trophoblastic neoplasia at a large tertiary centre in dubai. ISRN Obstet Gynecol. 2011; 2011: 453190[DOI][PubMed]
  • 5. Samal SK, Rathod S, Ghose S. Postmenopausal choriocarcinoma: A rare case report. J Midlife Health. 2014; 5(3): 159-61[DOI][PubMed]
  • 6. Wu W, Wang Y, Xu Y, Liu Y, Wang Y, Zhang H. Dysregulated activation of c-Src in gestational trophoblastic disease contributes to its aggressive progression. Placenta. 2014; 35(10): 824-30[DOI][PubMed]
  • 7. Chittenden B, Ahamed E, Maheshwari A. Choriocarcinoma in a postmenopausal woman. Obstet Gynecol. 2009; 114(2 Pt 2): 462-5[DOI][PubMed]
  • 8. O'Neill CJ, Houghton F, Clarke J, McCluggage WG. Uterine gestational choriocarcinoma developing after a long latent period in a postmenopausal woman: the value of DNA polymorphism studies. Int J Surg Pathol. 2008; 16(2): 226-9[DOI][PubMed]
  • 9. Kaabia O, Meddeb S, Rhim MS, Bibi M, Khairi H. The uterine choriocarcinoma in postmenopausal women: specificities of diagnosis and treatment. Pan Afr Med J. 2014; 19: 176[DOI][PubMed]
  • 10. Fisher RA, Savage PM, MacDermott C, Hook J, Sebire NJ, Lindsay I, et al. The impact of molecular genetic diagnosis on the management of women with hCG-producing malignancies. Gynecol Oncol. 2007; 107(3): 413-9[DOI][PubMed]
  • 11. Yousefi Z, Saeed SH, Tabatabaie A. Metastatic Choriocarcinoma in Postmenopausal Woman. Iran J Obstetr Gynecol Infertil. 2009; 4(26): 47-51
  • 12. Almasi A, Almassinokiani F, Akbari P. Frequency of molar pregnancies in health care centers of tehran, iran. J Reprod Infertil. 2014; 15(3): 157-60[PubMed]
  • 13. Garcia M, Romaguera RL, Gomez-Fernandez C. A hydatidiform mole in a postmenopausal woman. A case report and review of the literature. Arch Pathol Lab Med. 2004; 128(9): 1039-42[DOI][PubMed]
  • 14. Desai NR, Gupta S, Said R, Desai P, Dai Q. Choriocarcinoma in a 73-year-old woman: a case report and review of the literature. J Med Case Rep. 2010; 4: 379[DOI][PubMed]
  • 15. Evsen MS, Erdal SM, Ender SH, Senem S, Ugur F, Mehmet K. A Rare Case of Postmenopausal Bleeding: Choriocarcinoma. J Clin Gynecol Obstetr. 2012; 1[DOI]
  • 16. Bazinet R, Ibrahim AB, Campbell JS. Choriocarcinoma in a postmenopausal nulligravida. Can Med Assoc J. 1970; 102(2): 150-1[PubMed]
  • 17. Abike F, Temizkan O, Payasli A, Avsar F, Karahan N, Baspinar S. Postmenopausal complete hydatidiform mole: a case report. Maturitas. 2008; 59(1): 95-8[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments