International Journal of Cancer Management

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Postmenopausal Breast Cancer Risk in Relation to Antibodies Specific to Benzo[a]Pyrene, Estradiol and Progesterone

Andrew Glushkov 1 , 2 , Elena Polenok 1 , * , Mikhail Kostyanko 1 , 2 , Alexandr Antonov 3 , Natalia Verzhbitskaya 4 , Ilgiz Vafin 5 and Svetlana Ragozhina 5
Authors Information
1 Department of Molecular Human Ecology, Institute of Human Ecology Siberian Branch of Russian, Academy of Sciences, Kemerovo, Russia
2 Faculty of Biology, Kemerovo State University, Kemerovo, Russia
3 Regional Clinical Oncology Hospital, Kemerovo, Russia
4 Pathologoanatomic Bureaus, Kemerovo, Russia
5 Regional Center of Blood, Kemerovo, Russia
Article information
  • Iranian Journal of Cancer Prevention: April 30, 2016, 9 (2); e4212
  • Published Online: April 24, 2016
  • Article Type: Research Article
  • Received: October 3, 2015
  • Revised: November 10, 2015
  • Accepted: March 14, 2016
  • DOI: 10.17795/ijcp-4212

How to Cite: Glushkov A, Polenok E, Kostyanko M, Antonov A, Verzhbitskaya N, et al. Postmenopausal Breast Cancer Risk in Relation to Antibodies Specific to Benzo[a]Pyrene, Estradiol and Progesterone, Int J Cancer Manag. 2016 ; 9(2):e4212. doi: 10.17795/ijcp-4212.

Abstract
Copyright © 2016, Iranian Journal of Cancer Prevention. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Kahan Z, Thurzo L. [Breakthrough in breast cancer chemoprevention]. Orv Hetil. 2003; 144(13) : 597 -603 [PubMed]
  • 2. Sestak I. Preventative therapies for healthy women at high risk of breast cancer. Cancer Manag Res. 2014; 6 : 423 -30 [DOI][PubMed]
  • 3. el-Bayoumy K. Environmental carcinogens that may be involved in human breast cancer etiology. Chem Res Toxicol. 1992; 5(5) : 585 -90 [PubMed]
  • 4. Jeffy BD, Chirnomas RB, Romagnolo DF. Epigenetics of breast cancer: polycyclic aromatic hydrocarbons as risk factors. Environ Mol Mutagen. 2002; 39(2-3) : 235 -44 [PubMed]
  • 5. Rundle A, Tang D, Hibshoosh H, Schnabel F, Kelly A, Levine R, et al. Molecular epidemiologic studies of polycyclic aromatic hydrocarbon-DNA adducts and breast cancer. Environ Mol Mutagen. 2002; 39(2-3) : 201 -7 [PubMed]
  • 6. Lorand T, Vigh E, Garai J. Hormonal action of plant derived and anthropogenic non-steroidal estrogenic compounds: phytoestrogens and xenoestrogens. Curr Med Chem. 2010; 17(30) : 3542 -74 [PubMed]
  • 7. Albini A, Rosano C, Angelini G, Amaro A, Esposito AI, Maramotti S, et al. Exogenous hormonal regulation in breast cancer cells by phytoestrogens and endocrine disruptors. Curr Med Chem. 2014; 21(9) : 1129 -45 [PubMed]
  • 8. Moolten FL, Capparell NJ, Boger E, Mahathalang P. Induction of antibodies against carcinogenic polycyclic aromatic hydrocarbons. Nature. 1978; 272(5654) : 614 -6 [PubMed]
  • 9. Peck RM, Peck EB. Inhibition of chemically induced neoplasia by immunization with antigenic carcinogen-protein conjugate. Cancer Res. 1971; 31(11) : 1550 -4 [PubMed]
  • 10. Silbart LK, Rasmussen MV, Oliver AR. Immunoprophylactic intervention in chemical toxicity and carcinogenicity. Vet Hum Toxicol. 1997; 39(1) : 37 -43 [PubMed]
  • 11. Cernohorska H, Klimesova S, Lepsa L, Jinoch P, Milcova A, Schmuczerova J, et al. Influence of immunization with non-genotoxic PAH-KLH conjugates on the resistance of organisms exposed to benzo(a)pyrene. Mutat Res. 2012; 742(1-2) : 2 -10 [DOI][PubMed]
  • 12. Elsaesser F. Effects of active immunization against oestradiol-17 beta, testosterone or progesterone on receptivity in the female rabbit and evaluation of specificity. J Reprod Fertil. 1980; 58(1) : 213 -8 [PubMed]
  • 13. Rosenberg M, Amir D, Folman Y. The effect of active immunization against progesterone on plasma concentrations of total and free progesterone, estradiol-17beta and LH in the cyclic ewe. Theriogenology. 1987; 28(4) : 417 -26 [PubMed]
  • 14. Caldwell BV, Tillson SA, Esber H, Thorneycroft IH. Survival of tumours after immunization against oestrogens. Nature. 1971; 231(5298) : 118 -9 [PubMed]
  • 15. Petruzzelli S, Celi A, Pulera N, Baliva F, Viegi G, Carrozzi L, et al. Serum antibodies to benzo(a)pyrene diol epoxide-DNA adducts in the general population: effects of air pollution, tobacco smoking, and family history of lung diseases. Cancer Res. 1998; 58(18) : 4122 -6 [PubMed]
  • 16. Galati R, Zijno A, Crebelli R, Falasca G, Tomei F, Iecher F, et al. Detection of antibodies to the benzo(a)pyrene diol epoxide-DNA adducts in sera from individuals exposed to low doses of polycyclic aromatic hydrocarbons. J Exp Clin Cancer Res. 2001; 20(3) : 359 -64 [PubMed]
  • 17. Verdina A. Carcinogen-modified DNA and specific humoral immunity toward carcinogen-DNA adducts. A review. Ann Ist Super Sanita. 2006; 42(2) : 189 -94 [PubMed]
  • 18. Pauk N, Klimesova S, Kara J, Topinka J, Labaj J. The relevance of monitoring of antibodies against the polycyclic aromatic hydrocarbon (PAH) and PAH-DNA adducts in serum in relation to lung cancer and chronic obstructive pulmonary disease (COPD). Neoplasma. 2013; 60(2) : 182 -7 [PubMed]
  • 19. Ustinov VA, Matveeva VA, Kostyanko MA, Glushkov AN. Antibodies against benzo[a]pyrene in immunized mouse and in lung cancer patients. Exp Oncol. 2013; 35(3) : 207 -10 [PubMed]
  • 20. Glushkov AN, Polenok EG, Anosova TP, Savchenko YA, Bakanova ML, Minina VI. Serum antibodies to benzo [a] pyrene and chromosomal aberration in lymphocytes peripheral blood at the workers of coal processing enterprise. Rus J Immunol. 2011; 5 : 39 -44
  • 21. Glushkov AN, Polenok EG, Verzbitskaya NE, Varin IA, Ragozina SE. Antibodies to chemical carcinogens and steroid hormones in the lung cancer patients. Russ J Immunol. 2014; 8(2) : 219 -27
  • 22. Chagnaud JL, Faiderbe S, Geffard M. Identification and immunochemical characterization of IgA in sera of patients with mammary tumors. Int J Cancer. 1992; 50(3) : 395 -401 [PubMed]
  • 23. Glushkov AN, Anosova TP, Nebesnaya NG, Zheleznova LY. Isotipical special features of antibodies to polycyclic aromatic hydrocarbons in patients with cancer of mammary gland, stomach, colon and rectum. Exp Oncol. 1996; 18 : 426 -8
  • 24. Anosova TP, Polenok EG, Anosov MP, Krasilnikova KS, Kostyanko MV, Verzbitskaya NE. Antibodies to xeno- and endobiotics at the patients with breast cancer. Izvestiya Samara Science Center RAS. 2012; 5(2) : 440 -3
  • 25. Almasri NM, Al Hamad M. Immunohistochemical evaluation of human epidermal growth factor receptor 2 and estrogen and progesterone receptors in breast carcinoma in Jordan. Breast Cancer Res. 2005; 7(5) -604 [DOI][PubMed]
  • 26. Glushkov AN, Kostyanko MV, Cherno SV, Vasilchenko IL. Synthesis of polycyclic aromatic hydrocarbon-protein conjugates for preparation and immunoassay of antibodies. Russ J Immunol. 2002; 7(1) : 42 -6 [PubMed]
  • 27. Zweig MH, Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem. 1993; 39(4) : 561 -77 [PubMed]
  • 28. Zeleniuch-Jacquotte A, Shore RE, Koenig KL, Akhmedkhanov A, Afanasyeva Y, Kato I, et al. Postmenopausal levels of oestrogen, androgen, and SHBG and breast cancer: long-term results of a prospective study. Br J Cancer. 2004; 90(1) : 153 -9 [DOI][PubMed]
  • 29. Kaaks R, Rinaldi S, Key TJ, Berrino F, Peeters PH, Biessy C, et al. Postmenopausal serum androgens, oestrogens and breast cancer risk: the European prospective investigation into cancer and nutrition. Endocr Relat Cancer. 2005; 12(4) : 1071 -82 [DOI][PubMed]
  • 30. Curtis GL, Ryan WL, Stenback F. Antibody stimulation of benzo(a)pyrene carcinogenesis. Cancer Lett. 1978; 4(4) : 223 -8 [PubMed]
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