International Journal of Cancer Management

Published by: Kowsar

Clinicopathology Illustration Treatment Options and Survival in the Patients with Testicular Germ Cell Tumors in Kermanshah Province, Iran

Mehrdad Payandeh 1 , Nasrin Amirifard 1 , Edris Sadeghi 1 , * and Masoud Sadeghi 1
Authors Information
1 Cancer Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Article information
  • International Journal of Cancer Management: May 2017, 10 (5); e4039
  • Published Online: May 3, 2017
  • Article Type: Research Article
  • Received: October 3, 2015
  • Revised: September 7, 2016
  • Accepted: April 29, 2017
  • DOI: 10.5812/ijcm.4039

To Cite: Payandeh M, Amirifard N, Sadeghi E, Sadeghi M. Clinicopathology Illustration Treatment Options and Survival in the Patients with Testicular Germ Cell Tumors in Kermanshah Province, Iran, Int J Cancer Manag. 2017 ; 10(5):e4039. doi: 10.5812/ijcm.4039.

Copyright © 2017, International Journal of Cancer Management. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013; 63(1): 11-30[DOI][PubMed]
  • 2. Horwich A, Shipley J, Huddart R. Testicular germ-cell cancer. Lancet. 2006; 367(9512): 754-65[DOI][PubMed]
  • 3. Mortazavi N, Mahzooni P, Taheri D, Jalilian M, Novin K. Germ Cell Tumor's Survival Rate in Young Patients. Iran J Cancer Prev. 2015; 8(4): 3440[DOI][PubMed]
  • 4. Kobayashi K, Saito T, Kitamura Y, Nobushita T, Kawasaki T, Hara N, et al. Oncological outcomes in patients with stage I testicular seminoma and nonseminoma: pathological risk factors for relapse and feasibility of surveillance after orchiectomy. Diagn Pathol. 2013; 8: 57[DOI][PubMed]
  • 5. Bahrami A, Ro JY, Ayala AG. An overview of testicular germ cell tumors. Arch Pathol Lab Med. 2007; 131(8): 1267-80[DOI][PubMed]
  • 6. Beard CJ, Travis LB, Chen MH, Arvold ND, Nguyen PL, Martin NE, et al. Outcomes in stage I testicular seminoma: a population-based study of 9193 patients. Cancer. 2013; 119(15): 2771-7[DOI][PubMed]
  • 7. Sant M, Allemani C, Santaquilani M, Knijn A, Marchesi F, Capocaccia R, et al. EUROCARE-4. Survival of cancer patients diagnosed in 1995-1999. Results and commentary. Eur J Cancer. 2009; 45(6): 931-91[DOI][PubMed]
  • 8. Inci K, Dogan HS, Akdogan B, Ergen A, Tasar C, Ozen H. Does age affect the prognosis of patients with testicular germ cell tumor? Urol Int. 2007; 79(2): 117-23[DOI][PubMed]
  • 9. Dalal PU, Sohaib SA, Huddart R. Imaging of testicular germ cell tumours. Cancer Imaging. 2006; 6: 124-34[DOI][PubMed]
  • 10. Tan GH, Azrif M, Shamsul AS, Ho CC, Praveen S, Goh EH, et al. Clinicopathological features and survival of testicular tumours in a Southeast Asian university hospital: a ten-year review. Asian Pac J Cancer Prev. 2011; 12(10): 2727-30[PubMed]
  • 11. Chia VM, Quraishi SM, Devesa SS, Purdue MP, Cook MB, McGlynn KA. International trends in the incidence of testicular cancer, 1973-2002. Cancer Epidemiol Biomarkers Prev. 2010; 19(5): 1151-9[DOI][PubMed]
  • 12. Assi T, Rassy M, Nassereddine H, Sader-Ghorra C, Abadjian G, Ghosn M, et al. Distribution of testicular tumors in Lebanon: a single institution overview. Asian Pac J Cancer Prev. 2015; 16(8): 3443-6[PubMed]
  • 13. Chieffi P. Recent advances in molecular and cell biology of testicular germ-cell tumors. Int Rev Cell Mol Biol. 2014; 312: 79-100[DOI][PubMed]
  • 14. Magers MJ, Kao CS, Cole CD, Rice KR, Foster RS, Einhorn LH, et al. "Somatic-type" malignancies arising from testicular germ cell tumors: a clinicopathologic study of 124 cases with emphasis on glandular tumors supporting frequent yolk sac tumor origin. Am J Surg Pathol. 2014; 38(10): 1396-409[DOI][PubMed]
  • 15. Keskin S, Ekenel M, Basaran M, Bavbek S. Predictive value of marker half-life in relapsed and nonrelapsed nonseminomatous germ cell testicular tumor patients undergoing chemotherapy. Am J Clin Oncol. 2012; 35(4): 369-72[DOI][PubMed]
  • 16. Hemadi M, Zargar M, Sobhani A, Sobhani A. Assessment of morphological and functional changes in neonate vitrified testis grafts after host treatment with melatonin. Folia Morphol (Warsz). 2011; 70(2): 95-102[PubMed]
  • 17. Vogt AP, Chen Z, Osunkoya AO. Rete testis invasion by malignant germ cell tumor and/or intratubular germ cell neoplasia: what is the significance of this finding? Hum Pathol. 2010; 41(9): 1339-44[DOI][PubMed]
  • 18. Detti B, Elliott PA, McLaren DB, Howard GC. Late Relapse and Follow-up Protocols in Testicular Germ Cell Tumours: The Edinburgh Cancer Centre Experience and Review of the Literature. Clin Med Oncol. 2008; 2: 19-25[PubMed]
  • 19. Ozgun A, Karagoz B, Tuncel T, Emirzeoglu L, Celik S, Bilgi O. Clinicopathological features and survival of young Turkish patients with testicular germ cell tumors. Asian Pac J Cancer Prev. 2013; 14(11): 6889-92[PubMed]
  • 20. Kojima T, Kawai K, Tsuchiya K, Abe T, Shinohara N, Tanaka T, et al. Identification of a subgroup with worse prognosis among patients with poor-risk testicular germ cell tumor. Int J Urol. 2015; 22(10): 923-7[DOI][PubMed]
  • 21. Bokemeyer C, Harstrick A, Beyer J, Metzner B, Ruther U, Hartmann JT, et al. The use of dose-intensified chemotherapy in the treatment of metastatic nonseminomatous testicular germ cell tumors. German Testicular Cancer Study Group. Semin Oncol. 1998; 25(2 Suppl 4): 24-32[PubMed]
  • 22. Wang JW, Yang L, Wang JY, Qu T, Cai RG, Huang J, et al. [Long-term results of multimodality therapy of testicular germ cell tumor]. Zhonghua Zhong Liu Za Zhi. 2003; 25(4): 382-5[PubMed]
  • 23. Girones R, Aparicio J, Roure P, Germa-Lluch JR, Garcia Del Muro X, Vazquez-Estevez S, et al. Synchronous versus metachronous brain metastasis from testicular germ cell tumors (TGCT): an analysis from the Spanish Germ Cell Cancer Group data base. Clin Transl Oncol. 2014; 16(11): 959-65[DOI][PubMed]
  • 24. Salvati M, Piccirilli M, Raco A, Santoro A, Frati R, Lenzi J, et al. Brain metastasis from non-seminomatous germ cell tumors of the testis: indications for aggressive treatment. Neurosurg Rev. 2006; 29(2): 130-7[DOI][PubMed]
  • 25. Oechsle K, Bokemeyer C. Treatment of brain metastases from germ cell tumors. Hematol Oncol Clin North Am. 2011; 25(3): 605-13[DOI][PubMed]
  • 26. Brodsky GL. Pathology of testicular germ cell tumors. Hematol Oncol Clin North Am. 1991; 5(6): 1095-126[PubMed]
  • 27. Mann K. [Tumor markers in testicular cancer]. Urologe A. 1990; 29(2): 77-86[PubMed]
  • 28. Shin YS, Kim HJ. Current management of testicular cancer. Korean J Urol. 2013; 54(1): 2-10[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments