International Journal of Cancer Management

Published by: Kowsar

Suppressive Effect of Crocin and Cisplatin on Pluripotency Genes Expression in Human Cervical Cancer Cells

Homa Mollaei 1 , 2 , Mohammad Reza Abedini 1 and Reyhane Hoshyar 1 , *
Authors Information
1 Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, IR Iran
2 Department of Animal Biology, University of Tabriz, Tabriz, IR Iran
Article information
  • International Journal of Cancer Management: October 2017, 10 (10); e11152
  • Published Online: October 28, 2017
  • Article Type: Brief Report
  • Received: February 24, 2017
  • Revised: May 13, 2017
  • Accepted: October 15, 2017
  • DOI: 10.5812/ijcm.11152

To Cite: Mollaei H, Abedini M R, Hoshyar R. Suppressive Effect of Crocin and Cisplatin on Pluripotency Genes Expression in Human Cervical Cancer Cells, Int J Cancer Manag. 2017 ; 10(10):e11152. doi: 10.5812/ijcm.11152.

Abstract
Copyright © 2017, Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Obstetricians ACo Gynecologists. Diagnosis and treatment of cervical carcinomas. Washington (DC): American College of Obstetricians and Gynecologists (ACOG); 2002.
  • 2. He W, Li K, Wang F, Qin YR, Fan QX. Expression of OCT4 in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis. World J Gastroenterol. 2012;18(7):712-9. doi: 10.3748/wjg.v18.i7.712. [PubMed: 22363145].
  • 3. Tahmasebi MM, Sadeghizadeh M, Najafi F, Mowla SJ. Dendrosomal curcumin induced apoptosis by suppression of pluripotency genes in 5637 bladder cancer cells. Modares J Med Sci Pathobiol. 2013;16(1):23-39.
  • 4. Gazouli M, Roubelakis MG, Theodoropoulos GE, Papailiou J, Vaiopoulou A, Pappa KI, et al. OCT4 spliced variant OCT4B1 is expressed in human colorectal cancer. Mol Carcinog. 2012;51(2):165-73. doi: 10.1002/mc.20773. [PubMed: 21480394].
  • 5. Karoubi G, Gugger M, Schmid R, Dutly A. OCT4 expression in human non-small cell lung cancer: implications for therapeutic intervention. Interact Cardiovasc Thorac Surg. 2009;8(4):393-7. doi: 10.1510/icvts.2008.193995. [PubMed: 19126554].
  • 6. Leis O, Eguiara A, Lopez-Arribillaga E, Alberdi MJ, Hernandez-Garcia S, Elorriaga K, et al. Sox2 expression in breast tumours and activation in breast cancer stem cells. Oncogene. 2012;31(11):1354-65. doi: 10.1038/onc.2011.338. [PubMed: 21822303].
  • 7. Vishnoi K, Tyagi A, Singh SM, Das BC, Bharti AC. . Springer; 2015. Cervical Cancer Stem Cells and Their Association with Human Papillomavirus: Are They Ready as Anticancer Targets?Multi-Targeted Approach to Treatment of Cancer; p. 377-99.
  • 8. Liu XF, Yang WT, Xu R, Liu JT, Zheng PS. Cervical cancer cells with positive Sox2 expression exhibit the properties of cancer stem cells. PLoS One. 2014;9(1). e87092. doi: 10.1371/journal.pone.0087092. [PubMed: 24489842].
  • 9. Zhu H, Luo H, Zhang W, Shen Z, Hu X, Zhu X. Molecular mechanisms of cisplatin resistance in cervical cancer. Drug Des Devel Ther. 2016;10:1885-95. doi: 10.2147/DDDT.S106412. [PubMed: 27354763].
  • 10. Mostafavinia SE, Khorashadizadeh M, Hoshyar R. Antiproliferative and Proapoptotic Effects of Crocin Combined with Hyperthermia on Human Breast Cancer Cells. DNA Cell Biol. 2016;35(7):340-7. doi: 10.1089/dna.2015.3208. [PubMed: 27003728].
  • 11. Hoshyar R, Bathaie SZ, Sadeghizadeh M. Crocin triggers the apoptosis through increasing the Bax/Bcl-2 ratio and caspase activation in human gastric adenocarcinoma, AGS, cells. DNA Cell Biol. 2013;32(2):50-7. doi: 10.1089/dna.2012.1866. [PubMed: 23347444].
  • 12. Bolhasani A, Bathaie SZ, Yavari I, Moosavi-Movahedi AA, Ghaffari M. Separation and purification of some components of Iranian saffron. Asian J Chem. 2005;17(2):725.
  • 13. Behtash N, Karimi Zarchi M, Deldar M. Preoperative prognostic factors and effects of adjuvant therapy on outcomes of early stage cervical cancer in Iran. Asian Pac J Cancer Prev. 2009;10(4):613-8. [PubMed: 19827880].
  • 14. Hoshyar R, Mostafavinia SE, Bathaie SZ. Anticancer effects of saffron stigma (Crocus Sativus): a review study. Razi J Med Sci. 2016;22(140):69-78.
  • 15. Abdullaev FI, Espinosa-Aguirre JJ. Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials. Cancer Detect Prev. 2004;28(6):426-32. doi: 10.1016/j.cdp.2004.09.002. [PubMed: 15582266].
  • 16. Alavizadeh SH, Hosseinzadeh H. Bioactivity assessment and toxicity of crocin: a comprehensive review. Food Chem Toxicol. 2014;64:65-80. doi: 10.1016/j.fct.2013.11.016. [PubMed: 24275090].
  • 17. Jeter CR, Yang T, Wang J, Chao HP, Tang DG. Concise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding Questions. Stem Cells. 2015;33(8):2381-90. doi: 10.1002/stem.2007. [PubMed: 25821200].
  • 18. Wang ML, Chiou SH, Wu CW. Targeting cancer stem cells: emerging role of Nanog transcription factor. Onco Targets Ther. 2013;6:1207-20. doi: 10.2147/OTT.S38114. [PubMed: 24043946].
  • 19. Abedini MR, Muller EJ, Brun J, Bergeron R, Gray DA, Tsang BK. Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells. Cancer Res. 2008;68(12):4511-7. doi: 10.1158/0008-5472.CAN-08-0673. [PubMed: 18559494].
  • 20. Barr MP, Gray SG, Hoffmann AC, Hilger RA, Thomale J, O'Flaherty JD, et al. Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature. PLoS One. 2013;8(1). e54193. doi: 10.1371/journal.pone.0054193. [PubMed: 23349823].
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments