Comparison of Pap Smear Quality With Anatomical Spatula Method and the Common Method (SpatulaCytobrush): A Single Blind Clinical Trial

AUTHORS

Marzieh Soleimani 1 , * , Kh Abdali 1 , M Khajehei 2 , HR Tabatabaee 3 , PV Komar 4 , N Riaz Montazer 4

1 Dept. of Midwifery, Fatemeh College of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran

2 Dept. of Sexology, School of Public Health, Curtin University, Australia

3 ept. of Epidemiology, Health and Nutrition Faculty, Shiraz University of Medical Sciences, Shiraz, Iran

4 Medical Faculty, Shiraz University of Medical Sciences, Shiraz, Iran

How to Cite: Soleimani M , Abdali K, Khajehei M, Tabatabaee H, Komar P, et al. Comparison of Pap Smear Quality With Anatomical Spatula Method and the Common Method (SpatulaCytobrush): A Single Blind Clinical Trial, Int J Cancer Manag. 2012 ; 5(1):e80796.

ARTICLE INFORMATION

International Journal of Cancer Management: 5 (1); e80796
Published Online: March 31, 2012
Article Type: Research Article
Received: August 19, 2011
Accepted: October 20, 2011
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Abstract

Background: Cervical cancer is the third most common cancer in women in the world. Papanicolaou smear is known as a standard test for cervical cancer screening; however, the most important challenge is high rates of false negative results. The aim of this study was to compare the quality of smears obtained by anatomical spatula and spatula-cytobrush. The most important factor in false negative result is inappropriate tool of sampling.

Methods: One hundred married women participated in this single blind clinical trial. All participants were interviewed; two samples were obtained from every participant: one with spatula-cytobrush and another one with anatomical spatula. All slides were encoded and were assessed by two pathologists. Then, data were analyzed by means of kappa coefficient.

Results: Cell adequacy was 96.1 % in anatomical spatula method and 91.2 % in spatula-cytobrush method (p= 0.016). The rates for endocervical cells and metaplasia cells in anatomical spatula method were 70.6% and 24.5% respectively and these amounts were 69.6% and 24.5% respectively in the spatula-cytobrush method (p 0.05). Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).

Conclusion: Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatulacytobrush sampling.

© 2012, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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